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Spravato Treatment in Lincoln, NE

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Spravato Esketamine Treatment at Nebraska Peace of Mind

Traditional antidepressants do not work for everyone and can cause side effects that are hard to live with. Spravato (esketamine) offers a different, research-backed option for adults with treatment-resistant depression, working faster than most standard medications and supporting improvement over time.

Accepted Insurance Plans for Spravato

The list below applies to Spravato only and may be different from general medication management coverage:

  • UnitedHealthcare – Commercial
  • Blue Cross and Blue Shield of Nebraska – Nebraska Blue plans
  • Oscar Health Insurance – eligible plans per Oscar policy
  • Cigna – Commercial plans

Who Spravato May Help

Spravato is designed for adults who:

  • Have major depressive disorder (MDD)
  • Have not improved enough with at least two antidepressants, or could not tolerate them
  • Are 18 years or older
  • May have depressive symptoms with suicidal thoughts, under close medical supervision

During your assessment, we will review your history, current medications, and overall health to determine if Spravato is appropriate for you.

How Spravato Works

Spravato is a prescription nasal spray that targets the brain’s glutamate system and blocks certain NMDA receptors. This helps reset key pathways involved in mood and emotional regulation.

Unlike many traditional antidepressants that can take weeks to show benefit, Spravato can begin working within hours to days for some patients. It is given in a certified clinic under medical supervision and is typically used along with an oral antidepressant.

Why Patients Choose Our Program

  • Private, calm treatment rooms
  • A clinician or team member remains nearby and checks in regularly
  • Thoughtful, premium experience designed around comfort and safety
  • Benefits investigation and support with prior authorizations
  • Spravato is covered by many major insurance plans; we review costs up front

What to Expect During Spravato Treatment

  1. Initial consultation Your journey begins with a comprehensive evaluation. We review your mental health history, medications, medical conditions, and goals to see whether Spravato is a safe and appropriate option.
  2. In-clinic administration At your visit, you self-administer the Spravato nasal spray under the supervision of a trained clinician. You will be in a comfortable, dedicated treatment room designed for quiet and relaxation.
  3. Monitoring and support After dosing, you remain in the clinic for about two hours. We monitor your blood pressure, safety, and comfort, and check in with you throughout the session.
  4. Safe trip home You will not be able to drive the rest of the day. A trusted person or ride service is required to take you home after each treatment.
  5. Ongoing follow-up Your provider will meet with you regularly to track progress, adjust your plan as needed, and coordinate with your other clinicians when appropriate.

Typical Spravato Treatment Schedule

Your exact plan is personalized, but many adults with treatment-resistant depression follow a schedule similar to:

  • Weeks 1–4 Two sessions per week during the induction phase. Many patients begin to notice meaningful changes during this period.
  • Weeks 5–8 One session per week, as symptoms stabilize and we monitor your response.
  • Maintenance phase Sessions typically occur every one to two weeks, and sometimes less often over time, based on how you are doing.

Some patients are able, over time, to simplify their overall medication plan in coordination with their prescriber. Any changes to daily medications should always be made slowly and under medical supervision.

Advantages of Spravato Treatment

For individuals living with severe, persistent depression, Spravato can open the door to relief and renewed quality of life.

Faster-acting relief

Many patients experience symptom improvement within the first few weeks, and some notice changes within hours to days.

Research-backed outcomes

Clinical studies have shown continued benefit over weeks and months when Spravato is used as directed and monitored by a certified provider.

Covered by many insurers

Spravato is covered by many major insurance plans. Our team helps with benefits checks and prior authorizations so you know what to expect.

In-clinic support

Treatments take place in a supervised setting with continuous support from our team—no IV lines, no group rooms, and no being left alone.

Whole-person care

We focus on more than symptoms. Your Spravato plan is paired with ongoing psychiatric care, therapy, and lifestyle support whenever possible.

Explore Whether Spravato Is Right for You

If you feel like you have tried everything and still feel stuck, Spravato may be a next step to consider. Our team at Nebraska Peace of Mind is here to walk you through the process with care and clarity.

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Spravato offers hope to those with treatment-resistant depression (TRD) who have not found relief from conventional therapies and medications.

Typically taken with an oral antidepressant, Spravato can produce long-lasting results in just a few weeks.

Why choose Nebraska Peace of Mind for Spravato and psychiatric care?

A calm, trauma-informed experience with psychiatric specialists, integrated therapy, and care designed around you.

Feature Nebraska Peace of Mind Other Clinics
Covered by insurance and flexible payment options
✔️ Often covered
Spravato is covered by most major insurances. For those without coverage, we offer clear pricing and 0% payment plans through Cherry.
✖️ Limited options
Many clinics are cash-only or offer limited guidance around benefits and payment planning.
Constant in-person monitoring and support
✔️ You are never alone
A trained Spravato care team is present throughout your treatment, offering reassurance, safety, and support from start to finish.
✖️ Intermittent check-ins
Some clinics rely on call buttons or infrequent check-ins, which can feel isolating or disruptive.
Private, uninterrupted treatment space
✔️ Quiet and private
Spravato sessions are held in private rooms, designed for comfort and minimal interruption so you can fully focus on healing.
✖️ Less privacy
Shared spaces or frequent interruptions can make it harder to relax or feel emotionally safe.
Psychiatric specialists and team-based treatment planning
✔️ Specialist-led care
Your treatment plan is guided by psychiatric specialists and coordinated with your therapist or primary care when needed.
✖️ Limited involvement
Some centers offer minimal collaboration with your other providers, leading to fragmented care.
Integrated therapy and ongoing mental health care
✔️ Whole-person support
Access to therapists and psychiatric specialists under one roof, supporting you before, during, and after Spravato treatment.
✖️ Therapy not integrated
Many ketamine clinics do not offer in-house therapy or coordinated follow-up care.
Extra time for an unrushed, grounded experience
✔️ Not rushed
We build in time for check-in, treatment, and recovery so you do not feel hurried out the door.
✖️ Tight time slots
Strict schedules can feel rushed and leave less room for grounding and reflection.
Communication between sessions when you need it
✔️ Support that continues
Our team offers structured follow-up and clear ways to reach us between visits for questions or concerns.
✖️ Harder to reach
Some clinics are only accessible during brief visit windows, with limited follow-up.
Comfort-focused amenities and calming design
✔️ Designed for healing
A tranquil, spa-inspired environment with comfortable seating, soft lighting, and sensory-friendly touches to help you feel at ease.
✖️ More clinical feel
Many settings feel cold or purely medical, which can increase anxiety for patients.
Trauma-informed, mental-health-focused clinic
✔️ Psychiatry and therapy first
Nebraska Peace of Mind is dedicated to mental health, with a team experienced in trauma, mood disorders, anxiety, and complex cases.
✖️ Ketamine-only focus
Some clinics operate primarily as ketamine centers without a broader behavioral health ecosystem.
Comprehensive ADHD services for kids, teens, and adults
✔️ Assessment and ongoing care
Dedicated ADHD evaluations, medication management, and therapy to support focus, school success, work performance, and family life.
✖️ Limited ADHD support
Many ketamine-focused clinics do not provide full ADHD assessment, follow-up, and therapy in one place.
24/7 online booking and digital intake
✔️ On your schedule
Request appointments, complete paperwork, and join waitlists online any time of day from your phone, tablet, or computer.
✖️ Phone-only scheduling
Many clinics rely on limited phone hours, which can be hard to reach with work or school schedules.
High patient satisfaction and word-of-mouth referrals
✔️ Trusted by patients and families
Patients consistently share positive feedback about feeling heard, respected, and supported in their care at Nebraska Peace of Mind.
✖️ Variable experiences
Experiences at other clinics can be inconsistent, with less emphasis on relationship, follow-up, and long-term support.
Flexible scheduling options
✔️ Works with your life
A variety of appointment times, with efforts to accommodate work, school, and family schedules whenever possible.
✖️ Limited availability
Many clinics only offer standard weekday hours, making treatment harder to access.
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